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How Radiation Damages Our DNA And Causes Cancer

By Staff Curator / September 16, 2016

How much radiation has your body been exposed to through medical testing?

by: Samantha Debbie (naturalnews.com) –  Certain levels of radiation cause cancer – this is a well-established fact. However, what is less understood is how exactly radiation causes cancer to develop. New research published in the journal Nature Communications on September 12 sought to better understand this, and what they found is quite remarkable.

Researchers from the Wellcome Trust Sanger Institute, a non-profit that researches genetics and genomics in the United Kingdom were able to successfully identify two characteristics in human cancers associated with damage to DNA caused by ionizing radiation.

Using these “fingerprint patterns,” the scientists say doctors may be able to identify tumors caused by radiation and possibly treat them accordingly.

“Ionizing radiation, such as gamma rays, X-rays and radioactive particles can cause cancer by damaging DNA,” reports Medical Xpress. But researchers don’t understand exactly how this happens or how many tumors result from radiation exposure.

Researchers find mutational signatures in cancer cells caused by radiation

Past research has found that damage to human DNA tends to leave behind a “molecular fingerprint” or “mutational signature” that’s seen “on the genome of a cancer cell.

Using this information, scientists looked for these mutational signatures in 12 patients with secondary radiation-associated tumors, and compared them with 319 that were not exposed to radiation.

“To find out how radiation could cause cancer, we studied the genomes of cancers caused by radiation in comparison to tumours that arose spontaneously,” said Dr. Peter Campbell from the UK-based research institute.

“By comparing the DNA sequences we found two mutational signatures for radiation damage that were independent of cancer type. We then checked the findings with prostate cancers that had or…



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